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KMID : 0390020120220040422
Pediatric Allergy and Respiratory Disease
2012 Volume.22 No. 4 p.422 ~ p.427
A Case of Pulmonary Hemosiderosis that was Dissolved by an Oral Prednisolone and the Milk Avoidance
Kim Mi-Suk

Lee Ju-Kyung
Song Jun-Hyuk
Koh Young-Yull
Kim Woo-Sun
Choi Young-Hoon
Suh Dong-In
Abstract
A 29-month-old boy presented with fever, dyspnea, and paleness. He was initially diagnosed with pneumonia and severe sepsis. Although he was treated with intravenous antibiotics and high dose methylprednisolone, dyspnea and paleness recurred two times. Under suspicion of pulmonary hemosiderosis, we performed video-assisted thoracoscopic lung biopsy and bronchoalveolar lavage on him and found hemosiderin-laden macrophages in both specimens. Despite thorough history and laboratory examination, we could not find any pathologic or serologic evidence for primary and secondary causes of pulmonary hemosiderosis except for one that indicating Heiner`s syndrome. After taking oral prednisolone he showed improvement of anemia and dyspnea, which was maintained by milk avoidance. Based on the history and the existence of immunoglobulin G antibodies against milk components, we are considering it as the case of Heiner`s syndrome. [Pediatr Allergy Respir Dis(Korea) 2012;22:422-427]
KEYWORD
Pulmonary hemosiderosis, Milk allergy, Heiner`s syndrome, Avoidance
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